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内容简介
Authors Dave Nelson and Mike Cox combine the best of the laboratory and best of the classroom, introducing exciting new developments while communicating basic principles of biochemistry.
This comprehensive biochemical text covers all aspects of modern biochemistry, together with many new developments since the previous edition of four years ago.
Purpose: The goal is to provide students with a thorough biochemistry text. Given the overall importance of modern biochemistry (broadly writ), this is a worthwhile objective. In general, the goals are met.
The target audience includes senior undergraduate, graduate, and medical students. The authors are both knowledgeable and experienced.
There are several comprehensive biochemistry texts available. The fourth edition of Lehninger draws on a successful history initiated with the first edition which was a landmark text in its time. The 28 chapters follow an expected and logical progression from discussion of the fundamental molecules involved in cellular events through metabolism to the latest aspects of molecular biology. Illustrations are well done and frequent. Each chapter is accompanied by a short but useful bibliography and a set of problems. Problem answers are at the end, together with a detailed glossary and a thorough index. In an attempt to capture as broad a student audience as possible, discussions of both photosynthesis and metabolic diseases are offered. Thus, the material can be used in undergraduate/graduate courses as well as in medical school. As with other representatives of this text style, the typical student is likely to have some difficulty assigning relative importance to a given item considering the overall depth of coverage of topics. Nevertheless, careful reading with some guidance will be rewarding for most scholars and the book will serve as companion text for the usual biochemistry course. The bibliography is not as complete as some, but will provide pointers to additional material. A useful, albeit formidable (for the student) contribution.
This is yet another mega-text, seeking to satisfy all audiences. Not easy for the average student to read, but all of the material is there. Competitors include Voet and Voet, Biochemistry, 3rd edition (John Wiley & Sons, 2004); Devlin, Textbook of Biochemistry with Clinical Correlations, 6th edition (John Wiley & Sons, 2006) (medical focus); and Metzler, The Chemical Reactions of Living Cells, 2nd edition (Elsevier, 2003) (somewhat more comprehensive with an extraordinary bibliography). Is the new edition needed?? Probably, but most students will still be able to use the earlier version. Conversely, other publishers put out new editions, so this one has to.
作者简介
本书英文原著是一部阐明生物化学原理的科学名著，第1版发行于1982年。1993年出版的第2版，是对第1版的章节进行部分修改和重组。2000年出版的第3版，不仅对第2版的章节进行修改和重组，增加了新的内容，收入了很多全新的分子图形，而且全面概括了现代生物化学原理和技术的主要成就和最新进展。.
本书原著的优点是显而易见的。首先，它的内容比较全面。它包括4篇，第1篇为导论和一系列的背景知识介绍，第Ⅱ篇主要介绍细胞内分子的主要类型，第Ⅲ篇主要讲述中间代谢，第Ⅳ篇讨论了信息通路。其次，它的内容比较新颖。增加了关于生物信号的章节；讨论了肌红蛋白、血红蛋白、免疫球蛋白和肌肉的最新功能；加入了最新发展的代谢调节、酶和酶复合物的结构等方面的内容，还介绍了由代谢缺陷而导致的新疾病；氧化磷酸化和光合磷酸化的相关内容也已经重新改写，融人了新发现的膜结合酶复合物的结构和引人瞩目的ATP合成酶机制；系统地修改了遗传信息通路的章节，同时改进了编排／顷序。再者，本书引入了许多重要技术以阐明那些已经建立的概念和原理。新的方法主要包括NMR、质谱、SELEX和DNA微阵列等。最后，引入了许多大分子的结构图示，总共有超过1 000张的彩色图解(包括图表、照片、分子图形)，强调对基本原理的阐述，有助于读者深入地了解实验方法。...
Lehninger Principles of Biochemistry是2012年由W.H.Freeman出版,作者DavidL.Nelson。
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